Former House Speaker Nancy Pelosi’s stock portfolio has taken a major hit in 2025, aligning with the broader market sell-off.
To recap, Pelosi continued with her Congress trades in Q1 2025, adding five more equities to her portfolio, yet only one name stands out in profit: Tempus AI (NASDAQ: TEM).
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According to filings, TEM was part of Pelosi’s trades executed on January 14, 2025, and filed on January 17, 2025. The trades included a series of call option purchases across several major companies.
The U.S. lawmaker invested between $50,001 and $100,000 in Tempus AI. Since the purchase, the American health technology company’s stock has rallied 34%.
To put the gains into perspective, the benchmark S&P 500 index has plunged 13% since the politician’s transaction. As of press time, TEM was valued at $42.70, up 24% year-to-date.
The 2025 transactions also involved the accumulation of Amazon (NASDAQ: AMZN), Alphabet (NASDAQ: GOOGL), Nvidia (NASDAQ: NVDA), and Vistra (NYSE: VST).
However, as of the latest market data, four out of five investments are underwater, with losses ranging from 6.12% to 26.38%.
Why TEM stock has rallied
Generally, Tempus AI has benefited from the growing appetite for artificial intelligence (AI) applications in healthcare. Its focus on precision medicine, using AI to analyze vast clinical and molecular datasets, aligns with emerging industry trends.
At the same time, Tempus AI stock surged after the healthcare firm reported impressive Q4 2024 results and finalized a key acquisition. Revenue jumped 35.8% year-over-year to $200.7 million. Gross profit soared nearly 50%, and net losses narrowed significantly from $50.5 million to $13 million.
The February acquisition of Ambry Genetics further boosted investor confidence, strengthening Tempus AI’s position in genetic testing and precision medicine.
These fundamentals have partly informed Wall Street analysts at TipRanks‘ bullish outlook for TEM stock. According to nine experts, Tempus AI stock will likely trade at an average price of $64, with an upside of 50% in the next 12 months.
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