Tempus AI Inc. (NASDAQ: TEM), a stock closely watched due to its inclusion in Nancy Pelosi’s 2025 portfolio, is back in focus after insider filings revealed that two company directors offloaded more than $1.34 million worth of TEM shares in a single day.
According to Form 4 filings submitted to the Securities and Exchange Commission on April 3, Tempus AI board member and former FDA Commissioner Scott Gottlieb executed the largest trade, selling 27,837 shares at an average price of $47.21 on April 1, totaling approximately $1.31 million.
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The transaction was carried out under a Rule 10b5-1 trading plan, indicating it was pre-scheduled. On the same day, fellow director Jennifer A. Doudna offloaded 625 shares at an average of $48.12, bringing the combined sale to $1.34 million.

Pelosi’s position in TEM stock remains in the green
Meanwhile, Pelosi’s investment in Tempus AI remains her only profitable trade in 2025. As of market close on April 11, TEM shares were trading at $42.12, representing a 24% year-to-date gain.

In pre-market trading on April 14, the stock edged higher to $43.39, up 3.02%. However, it has declined approximately 10.8% since the insider selling took place on April 1.
Why are insiders dumping Tempus AI stock ?
This isn’t the first time that company insiders have engaged in concentrated selling activity. On February 20, six Tempus insiders offloaded shares worth a combined $26 million, followed by additional sales totaling around $4 million in March.
These successive rounds of insider selling have continued to draw attention, particularly as the stock has significantly pulled back from its 2025 peak of $88.94.
Like the earlier transactions, the April sales were largely conducted under pre-arranged Rule 10b5-1 trading plans, meaning they weren’t triggered by any sudden internal developments. Even so, the scale and timing of the April 1 liquidations with two directors selling more than $1.34 million in shares on the same day is notable.
While it’s normal for insiders to lock in gains after a major rally, the coordinated nature of the sales may suggest that key executives saw the recent run-up as an appropriate point to reduce exposure perhaps anticipating a period of price consolidation or tempered upside in the near term, especially considering the stock had already fallen nearly 47% from its February peak by the time these sales were executed.
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